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ea0019p56 | Clinical practice/governance and case reports | SFEBES2009

Pituitary ACTH-dependent Cushing’s syndrome caused by ectopic CRF secretion from an intra-adrenal phaeochromocytoma

Woods D , Arutchealvam V , Madathil A , Peaston R , Turner S , Neely RDG , Graham J , Richardson D , Lennard TJW , Bliss R , Bennett SB , Johnson S , Mason JI , Quinton R

A 69-year-old woman was admitted with new uncontrolled diabetes, severe hypertension and bilateral leg oedema. Cushings syndrome was suspected when she developed resistant hypokalemic alkalosis on diuretic therapy. Detailed questioning also revealed a history of episodic sweating, palpitation and tremor.Investigation & management: ACTH-dependant Cushings syndrome was confirmed: Serum ACTH 516 ng/l; urine free cortisol 20 045 nmol/24 h; 09...

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Endocrine Abstracts

Pituitary ACTH-dependent Cushing’s syndrome caused by ectopic CRF secretion from an intra-adrenal phaeochromocytoma

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